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Transient global amnesia patient handout8/31/2023 ![]() Our findings indicate that having an episode of TGA does not increase the risk of subsequent cerebrovascular events, seizures, or cognitive impairment.Ĭopyright © 2016 Mayo Foundation for Medical Education and Research. Transient global amnesia is a sudden, temporary loss of memory for events during, after, and sometimes before the event that caused the amnesia. Modified Rankin scale and death rates at last follow-up were also similar between both groups. The TGA recurrence occurred in 5.4% of patients after a median interval of 4.21 years (interquartile range, 2.82-8.44). There was no statistically significant difference between survival curves for the TGA group and the control group using time to any type of cerebrovascular event (log-rank P=.30), time to seizures event (log-rank P=.55), and time to cognitive impair event (log-rank P=.88) as end points. Previous migraine was more common in the TGA group (42 patients vs 12 patients P<.001). Prevalence of vascular risk factors and history of seizures were similar between both groups. A case-control comparison of 114 transient global amnesia (TGA) patients using both normal community-based controls (n 109) and transient ischaemic attack (TIA) controls (n 212) showed no. The mean duration of follow-up was 12 years in both groups (range, 0.07-29.93). End points were studied using Kaplan-Meier survival plots and log-rank test.Ī total of 221 patients with TGA were identified and 221 age- and sex-matched controls were included in the analysis. 2 Nevertheless, various etiological hypotheses, including arterial ischemia, migraine, venous reflux disorder, and seizure, have been presented. 1 The exact pathogenesis of TGA is unknown. End points were cerebrovascular event (stroke or transient ischemic attack), seizure, or cognitive impairment (mild cognitive impairment or dementia) during follow-up. Transient global amnesia (TGA) is a rare syndrome characterized by sudden onset of anterograde amnesia that universally lasts for up to 24 h. Transient global amnesia was defined clinically. Although patients may be disoriented, not know where they are or be confused about time, they are otherwise alert, attentive and have normal thinking abilities. To study the long-term risk of cerebrovascular events, seizures, and cognitive impairment in patients with transient global amnesia (TGA).ĭata for all patients diagnosed with possible TGA in Olmsted County, Minnesota, between January 1, 1985, through December 31, 2010, were retrieved from the Rochester Epidemiology Project database. Transient global amnesia (TGA) is a sudden, temporary interruption of short-term memory.
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